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All medicines had been discontinued, which include discomfort medication. The affected person claimed whole participation in typical tutorial and Actual physical functions. Magnetic resonance imaging (MRI) of The top at 8 months confirmed unchanged punctate subcortical white-make a difference hypodensities. Lower limb MRI at fourteen months showed

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Explanation The likelihood that the remedy effect described in a scientific overview approximates the truth depends upon the validity from the included research, as particular methodological features may very well be linked to outcome measurements.87 88 By way of example, trials with out documented enough allocation concealment exaggerate procedure

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